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Evaluation of perioperative landiolol administration for preventing atrial fibrillation during esophagectomy.

Evaluation of perioperative landiolol administration for preventing atrial fibrillation during esophagectomy. - Perioperative landiolol for preventing atrial fibrillation during esophagectomy.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000024040
Enrollment
188
Registered
2016-09-13
Start date
2016-09-06
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer(Esophagectomy)

Interventions

Landiolol administration Placebo administration

Sponsors

Shizuoka General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) surgery patients with histologically or cytologically confirmed esophageal cancer (2) patient age is below 20 years of age or older and 80 years of age at the time of obtaining informed consent (3) sufficient understanding of participation in the study, patients with written consent by the free will of the person has been obtained (4) surgery expression arthroscopic esophagus resection, the patient's stomach tube reconstruction

Exclusion criteria

Exclusion criteria: (1) history of arrhythmias (atrial fibrillation, atrioventricular block, etc.) (2) bradycardia from the preoperative period (heart rate 50 / min or less) (3) thyroid dysfunction (hyperthyroidism, hypothyroidism) (4) B blocker use from the preoperative period (5) history of asthma (6) heart failure hospitalizations, low cardiac function in the preoperative echocardiography (left ventricular ejection fraction less than 30%) (7) untreated pheochromocytoma

Design outcomes

Primary

MeasureTime frame
Perioperative atrial fibrillation incidence (within 96 hours)

Countries

Japan

Contacts

Public ContactYoshitaka Aoki

Shizuoka General Hospital Department of Anesthesiology

ysyaoki27@gmail.com054-247-6111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026