Healthy volunteers
Conditions
Interventions
once a day for five weeks
Placebo capsule once a day for five weeks
Sponsors
Ezaki Glico Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Men and women aged >= 30 to <50 years 2) Those fall under the category of Fizpatrick skintype II
Exclusion criteria
Exclusion criteria: 1) Those with a diagnosis of photosensitive disorder. 2) Those who take drugs which affect skin photosensitivity. 3) Those with diagnosis of diseases on the measurement region by a medical advice. 4) Those whose MED was not detected in the measurements. 5) Those who have treated for beauty on the measurement region. 6) Those who routinely take foods, supplements and cosmetics that contain the same active ingredient. 7) Those who have treated for special skincare on the mesurement region or who have a plan to have the treatment within past 4 weeks. 8) Those who changed healthy foods or external preparation including basic skin-care products that use for measurement region, or who have begun usage of them within past 4 weeks. 9) Those who was exposed to exceeded UV-light than in daily life by activities including long hours of outwork, sports, sea bathing and leisure activities, or who have a plan it during the study period. 10) Those who engage in the night work and work in shifts day and night. 11) Those who are receiving the treatments to treat or prevent disease at medical institution at the time of receiving informed consent, or who have need of those therapy. 12) Those who have serious disorders of carbohydrate metabolism, lipid metabolism, liver function, kidney function, heart, cardiovascular, respiratory organs, endocrine system and nervous system, or with a history of psychiatric disorder. 13) Those with a history of alcoholic and drug dependency. 14) Those with allergies to cosmetics or foods. 15) Pregnant women, those who may be pregnant, lactating women at the time of receiving informed consent, or women who hope to become pregnant during the study period. 16) Those who have participated in other human studies similar to the study within past 2 months. 17) Those who have participated in other human studies within the past 4 weeks, or who plan to participate. 18) Those who were considered inappropriate for the study by an investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Minimal Erythema Dose Minimal Tanning Dose Skin color (L*, a*) on the UV-irradiated region. Stratum corneum hydration and Transepidermal water loss on the UV-irradiated region. | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin color (L*, a*) Stratum corneum hydration Transepidermal water loss | — |
Countries
Japan
Contacts
Public ContactTakahiro Hemmi
Matsumoto Trading Co., Ltd. Safety Study Trust Dept.
Outcome results
None listed