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Effect of exercise training on exercise tolerance capacity,coronary microcirculation and adventitia in patients with vasospastic angina.

Effect of exercise training on exercise tolerance capacity,coronary microcirculation and adventitia in patients with vasospastic angina. - Exercise-VSA Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000023996
Enrollment
70
Registered
2016-09-09
Start date
2016-09-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vasospastic angina

Interventions

Patients with vasospastic angina are randomly assigned either to a training group or to an control group. Patients assigned to the training program are provided with a bicycle ergometer and instruct
t participated in training program.

Sponsors

Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1)Patients with vasospastic angina

Exclusion criteria

Exclusion criteria: (1) Acute coronary syndrome (2) EF is under 40%. (3) Severe renal failure. (4) Severe contrast media allergy (5) history of cardiac surgery (6) Severe asthma (7) Diabetes which needs insulin therapy (8) Patients with coronary artery stenosis>75% (9) Patients suspected exercise induced vasoconstriction (10) Patients with chronic obstructive pulmonary disease

Design outcomes

Primary

MeasureTime frame
(1)Change of exercise tolerance capacity assessed by cardiopulmonary testing.

Secondary

MeasureTime frame
(2)Coronary perivascular adipose tissue volume and myocardial circulation. (3)General blood examination data, Rho-kinase activity. (4)Change of QOL score assessed by questionnaire

Countries

Japan

Contacts

Public ContactYasuharu Matsumoto

Tohoku University Hospital Department of Cardiovascular Medicine

matsumoto@cardio.med.tohoku.ac.jp+81-22-717-7153

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026