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Prevalence and prognostic value of physical and social frailty in geriatric patients hospitalized for heart failure: A multicenter prospective cohort study

Prevalence and prognostic value of physical and social frailty in geriatric patients hospitalized for heart failure: A multicenter prospective cohort study - FRAGILE-HF

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000023929
Enrollment
1200
Registered
2016-09-05
Start date
2016-09-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart failure

Interventions

None listed

Sponsors

Department of Cardiology, The Sakakibara Heart Institute of Okayama
Lead Sponsor
Kameda Medical Center, Kitasato University Hospital, Kobe City Medical Center General Hospital, Nishiarai Heart Center Hospital, Juntendo University Hospital, Kitasato University Medical Center, Mitsui Memorial Hospital, Yokohama City University Medical Center, Tokai University Hospital, Shishu University Hospital, Saitama medical Center Jichi Medical University, Odawara City Hospital, and others
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: To determine the prevalence of the physical and social frailty among the patients with heart failure and their impact on the prognosis The patients who were admitted to each hospital due to heart failure (1) The diagnosis of heart failure is based on the Framingham criteria, which is stated in the guideline of Japanese Circulation Society (http://www.j-circ.or.jp/guideline/pdf/JCS2011_izumi_h.pdf ; last accessed August 7th, 2016). (2) The patients older than 64 years old are eligible (3) The patients who can walk by themselves (including the patients who can walk using a staff and so on) are eligible (who suffered in-hospital death will be excluded)

Exclusion criteria

Exclusion criteria: (1) The patients with low serum BNP (<100pg/ml) / NT-pro BNP (<300pg/ml) level on admission (2) The hemodialysis patients (including the patients planning to start hemodialysis) (3) The patients planning to undergo surgery for valvular heart disease or similar surgery (4) The patients who had undergone heart transplantation or the patients with ventricular assist devices (5) The patients with acute myocarditis (6) The patients who refused to participate in the study

Design outcomes

Primary

MeasureTime frame
All-cause mortality

Secondary

MeasureTime frame
Unexpected visit to the hospital, readmission due to heart failure, all-cause readmission, and so on.

Countries

Japan

Contacts

Public ContactNobuyuki Kagiyama / Yuya Matsue

The Sakakibara Heart Institute of Okayama / University of Groningen Department of Cardiology / Department of Cardiology

kgnb_27_hot@yahoo.co.jp086-225-7111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026