Keratosis
Conditions
Interventions
Apply topical prescribed drug for keratosis twice a day for 8 weeks.
Apply topical comparator product twice a day for 8 weeks.
Sponsors
Shiba Palace Clinic
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Japanese. 2) The persons who have dry and/or stiff feeling in the facial skin. 3) The persons who can peel off the goods for double eyelid at the time. 4) The persons who do not mind the base material and/or solvents adhere to the eyelashes at the time of the replica picking (, if the patients with eyelash extensions). 5) The persons with tending to stay indoors and who have no plans to go out (travel, business trip, etc) during the test period. 6) The persons who agree with the joining this study based on the consent by the document. 7) Patients with some keratosis on the test site (Corner of the eye and lower eyelid) that was diagnosed by the principal investigator or the sub-investigator. 8) Patients who do not have scratches, warts, pimples or burns on the test site, which might have negative impact in the evaluation and measurement. 9) Patients who have wrinkles on the test site, which belongs to the grade 3 to 6 ("Evaluation guidelines for the new efficacy acquisition of Anti-wrinkle product" published by Japanese cosmetic science society). 10) Patients who have the wrinkles belonging to similar grade in the left and right on the test site.
Exclusion criteria
Exclusion criteria: 1) Patients with history of allergy to cosmetics. 2) Patients who are receiving hormone replacement therapy. 3) Patients with experience of cosmetic medicine that might have negative impact on the test site. 4) Patients who are being treated with dermatology. 5) Pregnant or lactating patients. Patients with suspicion of pregnancy. 6) Patients who are participating in other clinical trials 7) Patients deemed inappropriate to participate in this study by the principal investigator or the sub-investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy (keratosis and wrinkle grade) and safety assessment of the test samples by the principal investigator or the sub-investigator before and after the four- and the eight-week application. | — |
Countries
Japan
Contacts
Public ContactMiwa Kaneko
SOUKEN CO., LTD Secretariat
Outcome results
None listed