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A randomized controlled study evaluating the efficacy and acceptability of split-dose compared with morning-only dose reduced-volume polyethylene glycol electrolyte solution for afternoon colonoscopy

A randomized controlled study evaluating the efficacy and acceptability of split-dose compared with morning-only dose reduced-volume polyethylene glycol electrolyte solution for afternoon colonoscopy - Split-dose vs morning-only dose preparation for afternoon colonoscopy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000023895
Enrollment
150
Registered
2016-10-01
Start date
2016-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inpatient who have a plan to be performed colonoscopy

Interventions

The standard regimen of PEG-ASC for afternoon colonoscopy in Japan is to take the first liter of PEG-ASC (250ml every 15 min) after 500 ml of clear liquid, and to take 500 ml of PEG-ASC after 250 ml o
The day before colonoscopy
To take the one liter of PEG-ASC (250ml every 15 min) after 500 ml of clear liquid from 4 PM. The day of colonoscopy
To take one liter of PEG-ASC (250ml every 15 min) after 500 ml of clear liquid from 9:45 AM.

Sponsors

Aichi Cancer Center Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients provided written, informed consent. All consecutive inpatients of both sexes aged 20 years and older who were scheduled for mainly therapeutic colonoscopy such as polypectomy, endoscopic mucosal resection, and endoscopic submucosal dissection at ACCH.

Exclusion criteria

Exclusion criteria: Patients with the following clinical features were excluded: significant cardiac, renal, hepatic, or metabolic co-morbidities, ascites, severe constipation (<2 bowel movements per week), known allergy to PEG-ELS, history of gastric stapling or bypass procedure, or history of prior colonic or rectal surgery. Patients were excluded if there was a suspected diagnosis of intestinal obstruction because of advanced colorectal cancer.

Design outcomes

Primary

MeasureTime frame
The primary endpoint was successful bowel cleansing.

Countries

Japan

Contacts

Public ContactMasahiro Tajika

Aichi Cancer Center Hospital Endoscopy

mtajika@aichi-cc.jp052-762-6111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026