A randamized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy of yogurt containing probiotic LKM512 and arginine on function of vascular endothelium and intestinal environment

A randamized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy of yogurt containing probiotic LKM512 and arginine on function of vascular endothelium and intestinal environment - Effects of yogurt containing probiotic LKM512 and arginine on function of vascular endothelium

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000023857

Enrollment

Registered

2016-08-31

Start date

2016-09-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

The volunteer were given a 12-week treatment with 100g yogurt containing bifidobacteria LKM512 (10 billion bacterial cells/100g) and arginine (600mg/100g) once a day. The volunteer were given a 12-w

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The individuals whose BMl is under 30

Exclusion criteria

Exclusion criteria: 1. Subjects who take a medicine, or visit the hospital for some disease 2. Subjects who had serious gastrointestinal disease, and subjects who had surgery of the digestive tract in the past 3. Subjects who was enrolled in other trails within one month, and female subjects who are, might become pregnant, or lactating 4. Subjects who have food allergies 5. Inappropriate cases evaluated by doctors

Design outcomes

Primary

Measure	Time frame
RH-PAT(Endo-PAT)	—

Secondary

Measure	Time frame
Blood biomarker, BMI, Systolic blood pressure, Diastolic blood pressure, Abdominal girth, Analyses of fecal samples	—

Countries

Japan

Contacts

Public ContactSatoshi Sakurai

imeQ CO. Ltd. CRO division

s-sakurai@imeq.co.jp03-6205-6222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026