Identification of circulating microRNAs as a biomarker of mental stress

Identification of circulating microRNAs as a biomarker of mental stress - Identification of circulating microRNAs as a biomarker of mental stress

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000023771

Enrollment

120

Registered

2016-09-15

Start date

2016-09-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastroesophageal reflux diseases

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Patient capable and willing of giving written informed consent - Outpatient of Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University Hospital - Patient who underwent esophagogastroduodenoscopy within the past 6 months - Patient taking proton pump inhibitors for more than 8 weeks for the treatment of gastroesophageal reflux symptoms

Exclusion criteria

Exclusion criteria: - Pregnant women - Patient who has a history of surgical operation in the esophagus, the stomach, the liver, the gallbladder, or the pancreas - Patient who underwent Helicobacter pylori eradication therapy within the past 1 year - Patient who has on organic disease associated with gastrointestinal symptoms, such as malignant diseases - Patient who has an psychiatric illness, such as schizophrenia and depression

Design outcomes

Primary

Measure	Time frame
The presence of circulating microRNAs which are associated with the severity of both mental stress (defined by HADS) and gastroesophageal reflux symptoms (defined by GerdQ)	—

Countries

Japan

Contacts

Public ContactTatsuhiro Masaoka

Keio University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine

masaoka@keio.jp03-3353-1211

Outcome results