refractory epilepsy
Conditions
Interventions
stiripentol 1000mg per day, oral twice-daily dosage at first medication dose up 500mg per day every week if no adverse effect, dose up until seizure is free, or up to 2500mg maximum dose per day
Sponsors
Nagoya City University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: autoimmune encephalitis is diagnosed in adult cases uncontrolled seizures are prolonged even treated with useful multiple antiepileptic drugs(AEDs), or no other AEDs can be medicated on account of drug allergy.
Exclusion criteria
Exclusion criteria: patients allergic to component of this drug pregnant or possibly pregnant women patients chief or sub investigator diagnose inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| neurological sign: continuous observation about presence or absence, frequency, and duration of seizures after medication | — |
Secondary
| Measure | Time frame |
|---|---|
| electroencephalogram(EEG): continuous observation about presence or absence of epileptic discharges in simple EEG fitted all the time, and 10-20 EEG at every two weeks after medication | — |
Countries
Japan
Contacts
Public ContactKenji Okita
Nagoya City University Department of Neurology
Outcome results
None listed