type 2 diabetes
Conditions
Interventions
None listed
Sponsors
Juntendo University Urayasu Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Men and women who were diagnosed with type 2 diabetes mellitus. Patients who are considered treatment with dapagliflozin is suitable. Patients with hypertention and/or abnormal electrocardiographic pattern. eGFR 45 ml/min/1.73 m2 <=
Exclusion criteria
Exclusion criteria: 1.Type 1 diabetes mellitus 2.Diabetic ketoacidosis, diabetic coma, or before coma 3.Sever infection, before and not long after surgery, or patients with sever trauma 4.Left ventricular dysfunction (EF < 50%) 5.Sever liver dysfunction 6.Past history of cerebral infarction, myocardial infarction, and sever heart failure 7.Women suspected of pregnancy or pregnant 8.Patients with a history of use SGLT2 inhibitors 9.Patients who have repeated urinary tract infections 10.Alchole intake excessive 11.Inadequate patients judged by doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of change in HbA1c after administration 24 weeks later | — |
Secondary
| Measure | Time frame |
|---|---|
| Body weight Blood pressure Serum lipid heart function (LVEF, E/A, E/e', DcT, LVMI,LAV) Urinary albumin excretion Urinary L-FABP excretion, serum cystatinC,eGFR Liver function(AST,ALT,gammaGTP) | — |
Countries
Japan
Contacts
Public ContactHajime M. Koyano
Juntendo University Urayasu Hospital Endocrinology and Diabetes
Outcome results
None listed