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Treatment and prognosis of heart valve registry

Treatment and prognosis of heart valve registry - Heart valve registry

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000023653
Enrollment
5000
Registered
2016-08-17
Start date
2013-04-22
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aortic stenosis/mitral regurgitation

Interventions

None listed

Sponsors

OCEAN-SHD organization
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patients who undergo transthoracic echocardiography at Keio University hospital and satisfy the following any items. A. A patient who has more than moderate aortic valvular stenosis B. A patient who has more than moderate mitral regurgitation

Exclusion criteria

Exclusion criteria: The patients who are under the 20 years old or who are found unfit to be respondent to a survey by physician-in-charge

Design outcomes

Primary

MeasureTime frame
During follow the natural history: 1. Mortality (all cause mortality, cardiovascular death, non-cardiovascular death) 2. Invasive procedure (surgical aortic valve replacement, mitral valve replacement, Transcatheter Aortic Valve Implantation, mitral valvuloplasty and Mitral Clip) 3. Admission of heart failure 4. Progression of heart valve by transthoracic echocardiography (increase of max velocity and pressure gradient, decrease of aortic valve area, and exacerbation of mitral regurgitation) After the invasive procedure: 1. Perioperative period: in-hospital death, complication (myocardial infarction, cardiac tamponade, vascular accident, auriculoventricular block for needing pacemaker, cerebral infarction, bleeding for needing blood transfusion) 2. Follow-up 1year, 2year, 3year, 4year, 5year after procedure: presence or absence of admission of heart failure, presence or absence of the death (cardiovascular death, non-cardiovascular death)

Countries

Japan

Contacts

Public ContactNobuhiro Yoshijima

Keio University Hospital Department of cardiology

nobuhiro_yossi@yahoo.co.jp03-3353-1211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 30, 2026