healthy senior subjects
Conditions
Interventions
We compare the blood kinetics with the group taken two pieces mucuna sheets (food processing thing) and four pieces.
For the next 12 weeks, we examine safety taken six pieces per a day.
Sponsors
Ehime University Graduate School of medicine Neurology and Clinical pharmacology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: general elderly people
Exclusion criteria
Exclusion criteria: The patients with Parkinson's disease The patients treated for thing antipsychotics treated for an antiparkinson agent There are a serious heart, lung, liver, renal dysfunction More than systolic blood pressure 180mmHg More than BMI 30 More than HbA1c 8.0 It is less than 8.0 mg/dl of hemoglobin, Less than 20000 platelet /mm3 AST, ALT, LDH, ALP, gGTP, BUN, a Cre level are less than eGFR 30ml/min more than 3 times of the normal upper limit level The AV block where is atrial fibrillation, 2 degrees or more with an electrocardiogram, the patients with a history of treatment of the malignant tumor within thing with the malignant tumor, the past five years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pharmacokinetics parameter of blood levodopa levels | — |
Secondary
| Measure | Time frame |
|---|---|
| Hypotensive effect, fatigue improved work, the Clinical Global Impressions (CGI) -ImprovementScale | — |
Countries
Japan
Contacts
Public ContactNoriko Nishikawa
Ehime University Graduate School of medicine Neurology and Clinical pharmacology
Outcome results
None listed