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Quantitative analysis of contrast-enhanced ultrasound using microbubble to detect micro-metastasis of lymph node in patients with breast cancer

Quantitative analysis of contrast-enhanced ultrasound using microbubble to detect micro-metastasis of lymph node in patients with breast cancer - Detection of micro-metastasis of lymph node in patients with breast cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000023614
Enrollment
90
Registered
2016-08-13
Start date
2013-11-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who will diagnosed with breast cancer, and will be performed radical breast surgery without neoadjuvant chemotherapy. Patients who will diagnosed with clinically negative lymph node metastasis by using preoperative palpation, CT and MRI.

Interventions

None listed

Sponsors

Diagnostic Radiology,Tohoku University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Patients who will be diagnosed with breast cancer and be performed radical breast surgery. Patients who will be performed surgery without neoadjuvant chemotherapy. Patients who will not be diagnosed with lymph node metastasis by palpation, CT and MRI.

Exclusion criteria

Exclusion criteria: Patients who will have possibility of pregnancy or patients who will be breast-feeding woman. Patients who will have allergy for contrast agent of ultrasound, egg and egg products. Patients who will have right-to-left shunt. Patients who will have severe heart disease or lung disease.

Design outcomes

Primary

MeasureTime frame
To evaluate whether the quantitative measurement of blood vessel density by contrast-enhanced ultrasound enables the diagnosis of lymph nodes micrometastases in breast cancer patients by setting appropriate threshold.

Countries

Japan

Contacts

Public ContactNaoko Mori

Tohoku University Graduate School of Medicine Department of Diagnostic Radiology

naokomori7127@gmail.com022-717-7312

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026