The relation between the long-term benefit of constraint-induced movement therapy and integrity of association fibers in chronic stroke patients: a pilot study

The relation between the long-term benefit of constraint-induced movement therapy and integrity of association fibers in chronic stroke patients: a pilot study - The relation between the long-term benefit of constraint-induced movement therapy and integrity of association fibers

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000023566

Enrollment

Registered

2016-08-09

Start date

2016-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Participants were chronic stroke patients (>7 months from stroke onset) with hemiparesis who received CIMT as part of their outpatient medical care at Hyogo College of Medicine Hospital between April 2010 and January 2016.

Exclusion criteria

Exclusion criteria: 1) age <20 years at time of treatment, 2) bilateral or brain stem infarct or hemorrhage, 3) voluntary extension <10 degree at metacarpophalangeal and interphalangeal joints of three or more fingers and voluntary extension <20 degree at one wrist, 4) severe balance or walking disorder, indicated by the need for assistance for standing, walking, or using the toilet, 5) substantial use of the affected upper extremity before the intervention, indicated by a score >2.5 points on the Amount of Use (AOU) scale of the Motor Activity Log (MAL), 6) clear signs of dementia or cognitive disorder, indicated by a score <24 points on the Mini-Mental State Examination), 7) severe aphasia or apraxia that inhibited performance of the intervention, 8) presence of another uncontrolled medical condition or severe end-stage disease, 9) severe contraction around the shoulder, elbow, wrist, or finger, 10) absence of magnetic resonance imaging (MRI) data before the intervention, and 11) missing clinical assessment data at the 6-month follow-up time point.

Design outcomes

Primary

Measure	Time frame
Fraction anisotropy value	—

Secondary

Measure	Time frame
Fugl-Meyer Assessment for upper extremitymotor activity log	—

Countries

Japan

Contacts

Public ContactTakashi Takebayashi

Graduate course in Hyogo college of medicine Department of rehabilitaiton science

takshi77@gmail.com0798-45-6388

Outcome results