Effect of intake of tablets or yogurt containing Lactobacillus rhamnosus L8020 on oral bacteria of children and disabilities

Effect of intake of tablets or yogurt containing Lactobacillus rhamnosus L8020 on oral bacteria of children and disabilities - Effect of Lactobacillus rhamnosus L8020 on oral bacteria

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000023503

Enrollment

180

Registered

2016-08-05

Start date

2016-05-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Caries Gingivitis, Periodontitis

Interventions

Volunteers ingest tablets-containing L8020 everyday after lunch for one month Volunteers ingest yogurt-containing L8020 everyday after lunch for one month Volunteers ingest yogurt-placebo everyday aft

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subject and parents of guardian who provide written informed consents

Exclusion criteria

Exclusion criteria: 1. Subject with allergy against dairy products or milk 2. Subject with a history of antibiotic treatment within a month before experiment 3. Subject who may receive treatments of topical fluoride or povidone-iodine during experiment period

Design outcomes

Primary

Measure	Time frame
Oral carriage of mutans streptococci Gingival Index	—

Secondary

Measure	Time frame
Oral status	—

Countries

Japan

Contacts

Public ContactTsuyoshi Taji

Integrated Health Sciences, Institute of Biomedical and Health Sciences, Hiroshima University Department of Oral Biology & Engineering

taji@hiroshima-u.ac.jp082-257-5797

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026