A prospective multicenter observational study of surgical palliation examining postoperative quality of life in patients treated for intestinal obstruction caused by peritoneal metastasis from incurable advanced gastric cancer

A prospective multicenter observational study of surgical palliation examining postoperative quality of life in patients treated for intestinal obstruction caused by peritoneal metastasis from incurable advanced gastric cancer - Peritoneal metastasis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000023495

Enrollment

100

Registered

2016-08-05

Start date

2013-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) histologically proven primary gastric adenocarcinoma presenting with intestinal obstruction diagnosed clinically, endoscopically, or radiographically (2) presence of non-curable factors confirmed by both enhanced abdominal computed tomography (CT) and exploratory laparoscopy or laparotomy; (3) no oral intake or extremely poor oral intake requiring parenteral nutrition (4) age of 20 years or more (5) surgically fit (6) Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0 through 2 (7) adequate organ function within 14 days before enrollment defined and (8) written informed consent (IC).

Exclusion criteria

Exclusion criteria: (1) active bleeding or perforation of the gastric tumour demanding an urgent surgery; (2) active coexisting cancer (synchronous coexisting cancer and recurrence of metachronous cancer) showing symptoms; (3) clinically suspected brain metastasis or carcinomatous meningitis; (4) presence of disseminated intravascular coagulation (DIC); and (5) severe mental disorder.

Design outcomes

Primary

Measure	Time frame
Changes in QOL for patients undergoing surgical palliation for GOO caused by incurable primary gastric cancer.	—

Secondary

Measure	Time frame
Postoperative improvement of oral intake, safety of surgical procedures, and postoperative overall survival.	—

Countries

Japan

Contacts

Public ContactKazumasa Fujitan, MD

Osaka Prefectural General Medical Center Surgery

fujitani@opho.go.jp06-6692-1201

Outcome results