Safety and efficacy of perioperative management using direct oral anticoagulants in patients on anticoagulant therapy

Safety and efficacy of perioperative management using direct oral anticoagulants in patients on anticoagulant therapy - Perioperative management using direct oral anticoagulants

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000023493

Enrollment

Registered

2016-08-05

Start date

2016-08-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Status requiring high-risk procedures in gastrointestinal tract during anticoagulant therapy

Interventions

perioperative management using direct oral anticoagulants in patients on anticoagulant therapy(-POD28)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Medical need of high-risk endoscopic procedures. 2. Comorbidity requiring antcoagulant therapy. 3. Age>=20 years. 4. Maintained major organ function. 5. Performance status(ECOG):0-2. 6. Informed consent.

Exclusion criteria

Exclusion criteria: 1. History of prosthetic heart valve replacement or rheumatic valvular disease. 2. Ccr<15ml/min. 3. Diagnosis of psychiatric diseases. 4. With active bacterial or fungus infection. 5. With uncontrollable hypertension. 6. Disqualified for the study by physicians.

Design outcomes

Primary

Measure	Time frame
Complication rate (bleeding and thromboembolism).	—

Countries

Japan

Contacts

Public ContactYoshito Hayashi

Osaka university graduate school of medicine Gastroenterology and hepatology

y.hayashi@gh.med.osaka-u.ac.jp06-6879-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026