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The effectivity of nifedipine ointment for anal fissures Comfiematory clinical trial

The effectivity of nifedipine ointment for anal fissures Comfiematory clinical trial - The effectivity of nifedipine ointment for anal fissures

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000023481
Enrollment
30
Registered
2016-08-04
Start date
2016-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anal fissure

Interventions

The patients put the nifedipine ointment on their anal verges once a day for 3 months.

Sponsors

Matsuda hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.over the age of twenty 2.the patients suffering from the pain or bleeding for the anal fissures 3.the patients suffering from the persisting pain despite of traditional treatments 4.the patients obtained the informed consent

Exclusion criteria

Exclusion criteria: 1.the patients who are unable to put the ointment to their anal verges 2.the patients who have the physical stenosis requiring surgical intervention 3.the patients who have the severe cardiovascular, blood, respiratory, neuropsychiatric, autimmune diseases 4.pregnancy or lactating women 5.the patients found inadequate for this study

Design outcomes

Primary

MeasureTime frame
the rate of improvement of the pain from the anal fissure after the use of the nifedipine ointment

Secondary

MeasureTime frame
the change of the maximum anal resting pressure and squeezing pressure bfore and after the therapy

Countries

Japan

Contacts

Public ContactYoshiko Aikawa

Matsuda hospital colo-proctology department

aiko-a@matsuda-hp.or.jp053-448-5121

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026