Healthy adults
Conditions
Interventions
Ingestion of 100 g of beverage containing probiotics daily for 12 weeks.
Ingestion of 100 g of beverage without probiotics daily for 12 weeks.
Sponsors
KSO Co., Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy men or women between the age of 20 and 64 years. 2. A fasting plasma glucose level of 110 mg/dL to 125 mg/dL and/or 2 hour plasma glucose level during OGTT of 140 mg/dL to 199 mg/dL. 3. Subjects giving written informed consent.
Exclusion criteria
Exclusion criteria: 1. Subjects routinely taking medicine as well as administration of medication which may influence blood glucose level. 2. Subjects routinely taking health food or supplement which may influence glucose metabolism. 3. Subjects with diabetes. 4. Subjects who are under medication or have serious diseases. 5. Subjects who have surgical history such as gastrointestinal disease. 6. Subject who regularly undertakes medication or treatment that affects bowel motion (such as: antibiotics, antiflatulents, laxatives, antidiarrheal drug). 7. Subjects who regularly consume functional food/nutraceuticals, health supplements (such as: lactic acid bacteria, bifidobacteria, oligosaccharides, dietary fiber) antiflatulents and/or laxatives in common use. 8. Subjects who habitually consume fermented foods during the study period. 9. Subjects who are under treatment or have a history of drug/alcohol dependence. 10. Subjects who are planned to become pregnant after informed consent for the current study or are pregnant or lactating. 11. Subjects with allergic to test products used in the study. 12. Subjects who participate in other clinical or plan to other clinical trials during this study period. 13. Subjects who are judged as unsuitable for the study by the investigator for other reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma glucose level and area under the curve of plasma glucose during 75 g oral glucose tolerance test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Insulin resistance, fasting blood glucose level, Hemoglobin A1c (HbA1c), blood short chain fatty acid, fecal bifidobacteria. | — |
Countries
Japan
Contacts
Public ContactEiji Yoshikawa
KSO Co., Ltd Sales department
Outcome results
None listed