Effects of Lactobacillus GG probiotics on the enterobacterial flora in patients with hematological diseases

Effects of Lactobacillus GG probiotics on the enterobacterial flora in patients with hematological diseases - Effects of LGG probiotics on patients with hematological diseases

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000023452

Enrollment

Registered

2017-08-02

Start date

2016-10-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematological diseases

Interventions

Participants will take a pack of test yogult at lunchtime for 2 weeks.Fecal samples will be analyzed before and once a week thereafter until hospital discharge.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with hematological diseases who are staying at East-9 ward of Osaka Saiseikai Nakatsu Hospital, who are expected to stay in the hospital for additional seven or more days, and who agreed and signed to the letter of consent.

Exclusion criteria

Exclusion criteria: Patients who have experienced severe adverse events by taking dairy products, or in whom oral intake is contraindicated due to clinical conditions.

Design outcomes

Primary

Measure	Time frame
Effects of LGG probiotics on composition and diversity of the enterobacterial flora evaluated with next-generation sequencer	—

Secondary

Measure	Time frame
Effects of LGG probiotics on viable bacteria, including multidrug-resistant strains, evaluated with fecal culture.	—

Countries

Japan

Contacts

Public ContactKensuke Ohta

Osaka Saiseikai Nakatsu Hospital Department of Hematology

kenohta@nakatsu.saiseikai.or.jp06-6372-0333

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026