A single arm confirmatory study of nivolumab in patients with previously treated advanced sarcomatoid carcinoma of the lung

A single arm confirmatory study of nivolumab in patients with previously treated advanced sarcomatoid carcinoma of the lung - Nivolumab for advanced sarcomatoid carcinoma of the lung

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000023433

Enrollment

Registered

2016-11-01

Start date

2017-03-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

advanced sarcomatoid carcinoma of the lung

Interventions

Nivolumab 3mg/kg every 2 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Histologically confirmed sarcomatoid carcinoma of the lung 2. Stage III, IV, and postoperative recurrence 3. Age > 20 4. PS 0-2 5. Measurable lesion 6. Adequate organ function 7. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Active auto-immune disease 2. Interstitial lung disease or pulmonary fibrosis 3. Active infection such as bacteria, HBV, or HCV

Design outcomes

Primary

Measure	Time frame
Overall response rate by Central review	—

Secondary

Measure	Time frame
Overall response rate by investigator, PFS, OS, DCR, Survival rate at 6 months, and toxicity	—

Countries

Japan

Contacts

Public ContactYutaka Fujiwara

National Cancer Center Hospital Department of Thoracic Oncology

yutakafu@ncc.go.jp03-3542-2511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026