Macula disease,Glaucoma
Conditions
Interventions
None listed
Sponsors
Topcon Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Subjects 20 years of age or older on the date of informed consent 2.Subjects able to understand the written informed consent and willing to participate as evidenced by signing the informed consent
Exclusion criteria
Exclusion criteria: 1.HFA visual field (24-2 Sita Standard, white on white) result unreliable (based on manufacturer's recommendation), defined as fixation losses > 20% or false positives> 33%, or false negatives> 33% 2.Visual field defects consistent with glaucomatous optic nerve damage based on with at least one of the following two findings: a)On pattern deviation (PD), there exists a cluster of 3 or more points in an expected location of the visual field depressed below the 5% level, at least 1 of which is depressed below the 1% level; b)Glaucoma hemi-field test "outside normal limits." 3.BCVA is worse than 20/25 4.SE > +5D or SE < -6D 5.Narrow angle with Shaffer grade 2 or less 6.Subject is not able to be measured axial legth 7.History of followed ocular pathology a)IOP > 22mmHg b)Disc hemorrhage c)Diabetic retinopathy d)Previous cataract surgery or refractive surgery e)Corneal pathology 8.Congenital anomaly of retina 9.History of diabetes, leukemia, dementia or multiple sclerosis (disease that produces defect of retinal nerve) 10.Subject with ocular media not sufficiently clear to obtain acceptable OCT images 11.Concomitant use of hydroxychloroquine and chloroquine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retina thickness (RNFLT, ILM-RPE thickness, Ganglion cell complex thickness etc.) | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between age distribution of retina thickness and age distributions of refraction, corneal curvature and axial length. | — |
Countries
Japan
Contacts
Public ContactAkihiko Sekine
Topcon Corporation Eye-care Business unit
Outcome results
None listed