Detection of carotid artery plaque in the blood flow due to new ultrasonic inspection method that does not use a contrast agent

Detection of carotid artery plaque in the blood flow due to new ultrasonic inspection method that does not use a contrast agent - Blood flow in the carotid artery plaque

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000023264

Enrollment

Registered

2016-07-21

Start date

2016-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotid atherosclerosis

Interventions

When admitted the blood flow in the plaque in the present study in the carotid artery echo test, the Perufurubutan 0.015ml / kg administered bolus, to record the same plaque in contrast harmonic mode.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Tokushima University Hospital in an enforcement plan to carotid endarterectomy, and patient consent was obtained for registration to the study at the time of carotid artery echocardiography.

Exclusion criteria

Exclusion criteria: Not obtained consent to the person or persons Daidaku Contraindication cases of contrast-enhanced ultrasonography enforcement (patient patient with a history of hypersensitivity to components of this drug, to eggs or egg products are allergic)

Design outcomes

Primary

Measure	Time frame
indicator of the carotid artery echocardiography plaque size, plaque brightness, plaque surface, blood flow degree, functional assessment items that are recommended in the guidelines, such as stenosis rate. contrast-enhanced ultrasonography assess the presence or absence of plaque in the blood flow signals in the contrast-enhanced ultrasonography. iPlaque tissue characterization evaluation of carotid artery plaque. CEA specimen compare the plaque within the blood flow at the resected specimen and each technique.	—

Measure

Time frame

indicator of the carotid artery echocardiography plaque size, plaque brightness, plaque surface, blood flow degree, functional assessment items that are recommended in the guidelines, such as stenosis rate. contrast-enhanced ultrasonography assess the presence or absence of plaque in the blood flow signals in the contrast-enhanced ultrasonography. iPlaque tissue characterization evaluation of carotid artery plaque. CEA specimen compare the plaque within the blood flow at the resected specimen and each technique.

—

Secondary

Measure	Time frame
Patients Background and history medical record ID, age, sex, body weight, the presence or absence of complications, history of allergy, history Cardiovascular disease valvular disease, cardiomyopathy, ischemic heart disease, arteriosclerosis obliterans, vasculitis, other Cardiovascular factors high blood pressure, diabetes, dyslipidemia, taste history oral medicine ACE, ARB, CCB, B-blocker, diuretics, statins, other. clinical examination blood count the number of white blood cells, red blood cell count, hemoglobin, platelet count, etc. Biochemistry hepatobiliary system, kidney, function indicator of the pancreas	—

Measure

Time frame

Patients Background and history medical record ID, age, sex, body weight, the presence or absence of complications, history of allergy, history Cardiovascular disease valvular disease, cardiomyopathy, ischemic heart disease, arteriosclerosis obliterans, vasculitis, other Cardiovascular factors high blood pressure, diabetes, dyslipidemia, taste history oral medicine ACE, ARB, CCB, B-blocker, diuretics, statins, other. clinical examination blood count the number of white blood cells, red blood cell count, hemoglobin, platelet count, etc. Biochemistry hepatobiliary system, kidney, function indicator of the pancreas

—

Countries

Japan

Contacts

Public ContactHirotsugu Yamada

Tokushima University Hospital Department of Cardiovascular internal medicine

yamadah@tokushima-u.ac.jp088-633-7851

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026