PhaseI/II prospective multi-center clinical trial of intra-arterial infusion of imipenem/cilastatin sodium particle for type1 complex regional pain syndrome in forward arm and hand

PhaseI/II prospective multi-center clinical trial of intra-arterial infusion of imipenem/cilastatin sodium particle for type1 complex regional pain syndrome in forward arm and hand - PhaseI/II study of intra-arterial infusion for CRPS1 in forward arm and hand

Status

Unknown

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000023254

Enrollment

Registered

2016-07-25

Start date

2016-07-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type1 complex regional pain syndrome in forward arm and hand

Interventions

Intra-arterial infusion using Imipenem/cilastatin sodium suspension

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Type1 CRPS in forward arm and hand with allodynia BPI average >5

Exclusion criteria

Exclusion criteria: passed more than 12months from onset severe arteriosclerosis HbA1C>8.5 the history of allergy to contrast enhance

Design outcomes

Primary

Measure	Time frame
Clinical response rate of pain relief at 4months after first treatment	—

Secondary

Measure	Time frame
Complication profile and its grade Change of BPI score Change of VAS score Grip power Quantity and frequency of other treatments Change of ROM Change of Quick Dash score Change of skin temperature	—

Countries

Japan

Contacts

Public ContactYuji Okuno

Edogawa Hospital Musculoskeletal Intervention Center

okuno@edogawa.or.jp03-3673-1221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026