Intraoperative Photodynamic Diagnosis study by fluorescent labeling with 5-aminolevulinic acid in Endocrine Surgery

Intraoperative Photodynamic Diagnosis study by fluorescent labeling with 5-aminolevulinic acid in Endocrine Surgery - IPDES

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000023246

Enrollment

Registered

2016-08-01

Start date

2016-05-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid, parathyroid and adrenal diseases

Interventions

Administering 5ALA method

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are sufficiently explained and agreed with this experiment by written documents. Female or male above 20 years old.

Exclusion criteria

Exclusion criteria: Patients who are contraindication to aminolevulinic acid. Patients who have cardiovascular disease, liver dysfunction or kidney disease. Patients who are under 20 years old, expectant or nursing mothers are excluded. Patients who take medication or food associated with the risk for the onset of photo-hypersensitivity with 5-ALA.

Design outcomes

Primary

Measure	Time frame
To identify the parathyroid gland or adrenal medulla intraoperatively. To evaluate if there is no severe organ dysfunction by administering 5-ALA.	—

Secondary

Measure	Time frame
To evaluate the parathyroid gland or the adrenal cortex gland are not detected in histopathology of surgically removed specimen.	—

Countries

Japan

Contacts

Public ContactRitsuko Okamura

Nippon Medical School Endocrine Surgery

ritsuokamura@gmail.com03-5814-6219

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026