Effects of local anesthetics with adrenaline or felypressin on the QTc interval in elderly: a randomized double-blind crossover study.

Effects of local anesthetics with adrenaline or felypressin on the QTc interval in elderly: a randomized double-blind crossover study. - The effect of local anesthetics with adrenalin or felypressin on the QTc interval in elderly

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000023236

Enrollment

Registered

2016-10-01

Start date

2016-09-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elderly aged over 65 years

Interventions

The intervention of this study is the administration of local anesthetics with adrenalin as an infiltration anesthesia The intervention of this study is the administration of local anesthetics with fe

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Elderly patients who visited Special care clinic-1 in Tokyo Medical and Dental University 2.Elderly patients undergoing two or more teeth extraction 3.Elderly patients with ASA physical status II-III 4.Elderly patients who are able to understand and subscribe to our informed consent

Exclusion criteria

Exclusion criteria: 1. Elderly patient with a history of tachyarrhythmia 2. Elderly patient with severe renal or liver dysfunction. 3.Elderly patient with QT prolongation in the preoperative electrocardiogram

Design outcomes

Primary

Measure	Time frame
QTc interval	—

Countries

Japan

Contacts

Public ContactYuka Kyosaka

Tokyo Medical and Dental University Gerodontology and Oral Rehabilitation, Department of Gerontology and Gerodontology, Graduate Schoo

shika.qq@gmail.com03-5803-5561

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026