hip osteoarthritis
Conditions
Interventions
The computer randomly assign patients to the dexmedetomidine group (group D, n=26) or the propofol group (group P, n=26). Anesthesiologist is blinded from the administration. Evaluation of the quality
s Assessment of Alertness/Sedation Scale (OAA/S). Group D receive dexmedetomidine at a loading dose of 6 mcg/kg/hr for 10 minutes followed by 0.2-0.7mcg/kg/hr infusion until the OAA/S score reached 2-
10cm-scale where 0 = no pain and 10 = worst pain).
Anesthesiologist is blinded from the administration. Evaluation of the quality of sedation are based on an
Sponsors
Asahikawa Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who have total hip arthroplasty by general anesthesia using lumbar plexus block
Exclusion criteria
Exclusion criteria: Patients who have had alpha 2 agonist and/or antagonist, same side hip operation before the operation, anatomical abnormalities at their loins, neurological abnormalities, severe heart and/or renal failure, vasopressors in the operation, continuous unstable hemodynamic parameter (sBP>200, sBP<80, HR<40), disagreement with our study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score(VAS) 24 hour after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score(VAS) soon, 4 hour, and 48hour after surgery Timing of getting out of bed, satisfaction, the amount of analgesics | — |
Countries
Japan
Contacts
Public ContactMasahiro Tada
Asahikawa Medical University Department of Anesthesiology and Critical Care Medicine
Outcome results
None listed