Pancreatic cancer
Conditions
Interventions
Conversion surgery after Chemotherapy and Radiochemotherapy
Sponsors
Ochanomizu Gastrointestinal Oncology Group
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) It is histologically or cytologically diagnosed as pancreatic cancer. 2) Unresectable locally advanced pancreatic cancer according to NCCN guideline 2016 3) Age from 20 to 80 years. 4) ECOG performance status of 0 or 1 5) No previous treatment 6) Labo data to entry satisfy following criteria 1. White blood cell >=3,500/mm3, <12,000/mm3 2. Neutro >=2000/mm3 3. Hb >=9.0/dl 4. T-Bil<=2.0mg/dl (<=3.0mg/dl, after biliary drainage) 5. AST and ALT<=150IU/l 6. serum creatinine<=1.2mg/dl 7. eGFR>=60ml/min 7) Written informed consent
Exclusion criteria
Exclusion criteria: 1) -1 Initially diagnosed as resectable pancreatic cancer -2 Initially diagnosed as unresectable pancreatic cancer with distant metastasis 2) Age: over 80 years, or less than 20 years 3) ECOG performance status =>2 4) Previous treatments 5) Labodata do not satisfy inclusion criteria 6) No written informed consent 7) Inadequate physical condition, as diagnosed by primary physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The R0 resection rate | — |
Countries
Japan
Contacts
Public ContactDaisuke Ban
Tokyo Medical and Dental University Hepatobiliary and Pancreatic Surgery
Outcome results
None listed