A Feasibility study of the nutritional and exercise treatment for the elderly patients with advanced non-small-cell lung and pancreatic cancer

Conditions

Non-small-cell lung and pancreatic cancer

Naito T, Okayama T, Aoyama T, Ohashi T, Masuda Y, Kimura M, Shiozaki H, Murakami H, Kenmotsu H, Taira T, Ono A, Wakuda K, Imai H, Oyakawa T, Ishii T, Omori S, Nakashima K, Endo M, Omae K, Mori K, Yamamoto N, Tanuma A, Takahashi T.

2017-11-2844 citations

10.1186/s12885-017-3795-2

Skeletal muscle depletion during chemotherapy has a large impact on physical function in elderly Japanese patients with advanced non-small-cell lung cancer.

Naito T, Okayama T, Aoyama T, Ohashi T, Masuda Y, Kimura M, Shiozaki H, Murakami H, Kenmotsu H, Taira T, Ono A, Wakuda K, Imai H, Oyakawa T, Ishii T, Omori S, Nakashima K, Endo M, Omae K, Mori K, Yamamoto N, Tanuma A, Takahashi T.

2017-08-2555 citations

10.1186/s12885-017-3562-4

Interventions

early multimodal intervention (nutritional intervention, home-based muscle training, and lifestyle intervention to promote physical activity)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) >=70 years old and ECOG-PS 0-1 2) newly diagnosed NSCLC/pancreatic cancer in stage III, IV, or post-operative recurrence. 3) They are planned to receive the first-line systemic chemotherapy 4) Having written informed consent 5) Brathel index >= 95 points 6) More than 3 months of survival was expected

Exclusion criteria

Exclusion criteria: 1) Having high risks for safe physical assessments and interventions (e.g. Unstable cardiac diseases, Severely symptomatic brain or bone mets, severe phyciatric disease, etc) 2) Having difficulties in swallowing, digesting, and absorbing food

Design outcomes

Primary

Measure	Time frame
attendance rate for exercise and nutritional sessions in 8 weeks	—

Secondary

Measure	Time frame
safety, adverse events, compliance	—

Countries

Japan

Contacts

Public ContactTateaki Naito

Shizuoka Cancer Center Division of Thoracic Oncology

t.naito@scchr.jp055-989-5222

Outcome results

None listed