A prospective, observational study to compare pre- with intra-anesthetic airway resistance in patients scheduled for surgery under general anesthesia, using the information on flow-volume curves obtained prior to and during general anesthesia.

A prospective, observational study to compare pre- with intra-anesthetic airway resistance in patients scheduled for surgery under general anesthesia, using the information on flow-volume curves obtained prior to and during general anesthesia. - A prospective, observational study to compare pre- with intra-anesthetic airway resistance in patients scheduled for surgery under general anesthesia, using the information on flow-volume curves obtained prior to and during general anesthesia.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000023180

Enrollment

500

Registered

2016-07-17

Start date

2016-04-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Not applicable (This is a prospective, observational study involving patients scheduled for surgery under general anesthesia.)

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients scheduled for open or laparoscopic abdominal, open or laparoscopic gynecological, neurosurgical, orthopedic, ontological, ophthalmic, plastic and dental operation under general anesthesia, all of whose airways are managed by orotracheal intubation with the use of a normal or spiral endotracheal tube.

Exclusion criteria

Exclusion criteria: Patients scheduled for cardiac and respiratory surgery. Patients undergoing general anesthesia using a double lumen endotracheal tube, a RAE endotracheal tube and a supraglottic airway devise.

Design outcomes

Primary

Measure	Time frame
Pre- and intra-anesthetic airway resistance calculated based on the slopes of flow-volume curves obtained prior to and during general anesthesia. Static lung compliance calculated as the ratio between VT and plateau pressure minus PEEP.	—

Secondary

Measure	Time frame
Endotracheal tube resistance measured based on the relationship between pressure drop and flow within a certain range of flow rates.	—

Countries

Japan

Contacts

Public ContactTakamistu Ikeda

The University of Tokyo Hospital Department of Anesthesiology

voice_575@live.jp+81-3-3815-5411

Outcome results