Parkinson'
Conditions
Interventions
Sponsors
Juntendo University School of Medicine, Department of Neurology
SENDAI NISHITAGA NATIONAL HOSPITAL T.Hasegawa CO.,LTD
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Patients with Parkinson's disease; MDS clinical diagnostic criteria for Parkinson's disease 2)No change in Anti-parkinsonian medications over 4 weeks 3)Lower than Modified Hoehn and Yahr stage 4 4)Mini Mental State Examination over 20, lower than 26 5)Inpatients or outpatients 6)Living with their caregivers 7)Age over 19, both women and men 8)Agreed with signed consent form
Exclusion criteria
Exclusion criteria: 1)dementia or person who cannot understand the way of olfactory training 2)Patients with Parkinsonism 3)Modified Hoehn & Yahr stage 5 4)abnormal olfactory function based on ENT problem, or sever cardiac, pulmonary, liver, gastrointestinal disease. 5)patients with carcinoma 6)pregnancy 7)allergy 8)person who are considered to be inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of change in Japanese version of Montreal congnitive Assessment(MOCA-J) between first week and 12weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS),The Odor Stick Identification Test for the Japanese (OSIT-J), MMSE, Beck Depression Inventory (BDI), Parkinson's Disease Questionnaire-39 (PDQ-39),T&T olfactometry.These rates of change between first week and 12weeks. 2)Duration until stopping the study due to change of anti-Parkinsonian medications 3)Otorhinolaryngology examination | — |
Countries
Japan
Contacts
Public ContactMayuko Ogawa
Juntendo University School of Medicine Department of Neurology
Outcome results
None listed