Periodontal disease
Conditions
Interventions
Brushing with a dentifrice (OC1510) offered to participants for 28 days.
Sponsors
Department of Periodontology, Tokyo Dental College
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Those who agreed to participate in the study with written informed consent. 2. The SPT patients with mild to moderate periodontitis at least one site with PD >=4 mm and GI1 or GI2.
Exclusion criteria
Exclusion criteria: 1. Those with uncontrolled systemic diseases (ex. diabetes, hyperlipidemia, cardiovascular diseases, osteoporosis, autoimmune diseases) 2. Those with severe dental problems not suitable for this study 3. Those under periodontal therapy 4. Smokers 5. History of antimicrobial treatment or taking dietary supplements within 3 months 6. Those who received SRP within 3 months 7. Those who are already using a similar to present investigational dentifrice 8. Those who are judged as inappropriate by an attending dentist
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing depth | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical attachment level Plaque Index Gingival Index Gingival swelling Gingival redness Inflammatory markers of gingival crevicular fluid (GCF) Periodontal pathogens | — |
Countries
Japan
Contacts
Public ContactTakashi Kinumatsu
Tokyo Dental College Department of Periodontology
Outcome results
None listed