Efficacy of line-assisted complete closure of large colorectal mucosal defects after endoscopic submucosal dissection: a randomized controlled trial

Efficacy of line-assisted complete closure of large colorectal mucosal defects after endoscopic submucosal dissection: a randomized controlled trial - LACC trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000023107

Enrollment

Registered

2016-07-13

Start date

2016-07-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal neoplasm

Interventions

Non-closure group Line-assisted complete closure group

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women Lesions are located at the Cecum or Ascending colon Large mucosal defect after colonic ESD

Exclusion criteria

Exclusion criteria: Lesions invaded at the appendiceal orifice or ileocecal valve Patients with intra-operative perforation Patients with severe organ failure Patients who have been judged as in appropriate for this study

Design outcomes

Primary

Measure	Time frame
Proportion of post-ESD coagulation syndrome	—

Secondary

Measure	Time frame
Proportion of delayed perforation Proportion of delayed bleeding Success rate of LACC Procedure time of LACC Length of hospital stay	—

Countries

Japan

Contacts

Public ContactYasushi Yamasaki

Osaka Medical Center for Cancer and Cardiovascular Diseases Department of Gastrointestinal Oncology

yamazaki-ya@mc.pref.osaka.jp+81-6-6972-1181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026