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Functional MRI study of treatment mechanisms of Eye Movement Desensitization and Reprocessing in Posttraumatic stress disorder

Functional MRI study of treatment mechanisms of Eye Movement Desensitization and Reprocessing in Posttraumatic stress disorder - Functional MRI study of treatment mechanisms of EMDR in PTSD

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000023104
Enrollment
20
Registered
2016-07-15
Start date
2015-07-30
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Posttraumatic stress disorder

Interventions

fMRI measurements during the script-driven imagery task and EMDR treatment/Patients with PTSD fMRI measurements during the script-driven imagery task/Normal controls

Sponsors

Hamamatsu University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.To meet the diagnostic criteria for Posttraumatic stress disorder in DSM-5 as a primary diagnostic 2.Aged 18 to 65 years old 3.Subjects who have signed consent to participate in this study

Exclusion criteria

Exclusion criteria: 1.Prior treatment of EMDR. 2.Subjects who have any other current DSM-5 diagnosis of the following;"Neurodvelopmental Disorders","Schizophrenia Spectrum and other Psychotic Disorders","Bipolar and Related Disorders","Feeding and Eating Disorders","Substance-Related and Addictive Disorders","Neurocognitive Disoreders". 3.Subjects who have a diagnosis of a severe physical disorder. 4.Women during pregnancy, possible pregnancy. 5.Subjects who have serious suicidal ideation. 6.Subjects with metallic device in their body. 7.Inappropriate patients for this study judged by physician.

Design outcomes

Primary

MeasureTime frame
Brain function with fMRI during a script-driven imagery task before and after EMDR treatment

Secondary

MeasureTime frame
Clinician-Administered PTSD Dessosiative Experiences Scale-2 Impact of Event Scale-revised Beck Depression Inventory-2 State-Trait Anxiety Inventory Posttraumatic Cognition Inventory Posttraumatic Growth Inventory

Countries

Japan

Contacts

Public ContactJUN INOUE

Hamamatsu University School of Medicine Department of Child and Adolescent Psychiatry

juninoue@hama-med.ac.jp053-435-2295

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026