Study on the uneven CSF distribution, cerebral white matter damage and L-PGDS in idiopathic normal pressure hydrocephalus

Study on the uneven CSF distribution, cerebral white matter damage and L-PGDS in idiopathic normal pressure hydrocephalus - Study on the brain imaging and L-PGDS in iNPH

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000023063

Enrollment

Registered

2016-07-11

Start date

2016-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic normal pressure hydrocephalus

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with one of cardinal three symptoms (gait, bladder, cognition) and cerebral ventriculomegaly.

Exclusion criteria

Exclusion criteria: Contraindication of lumber puncture.

Design outcomes

Primary

Measure	Time frame
Symptoms (iNPHGS/FAB/MMSE/TUG/MDS_UPDRS)	—

Secondary

Measure	Time frame
CSF markers (L-PGDS/Tau/Abeta) MRI (ARWMC scores/FA/MD) Sleep (PSQI/ESS/polysomnography)	—

Countries

Japan

Contacts

Public ContactNamiko Nishida

Tazuke Kofukai Medical Research Institute Kitano Hospital Department of Neurosurgery

n-nishida@kitano-hp.or.jp06-6312-1221

Outcome results