Analgesic effects of Ivabradine on inflammatory pain in healthy volunteers

Analgesic effects of Ivabradine on inflammatory pain in healthy volunteers - Analgesic effects of Ivabradine on inflammatory pain

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000023022

Enrollment

Registered

2016-09-01

Start date

2016-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy volunteers

Interventions

Oral administration of Ivabradine (5-15 mg) for 2 days Oral administration of Placebo for 2 days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: healthy adults volunteers

Exclusion criteria

Exclusion criteria: chronic pain history of heart failure electrocardiogram abnormality pregnant female regular use of analgesics neurologic deficits psychotic and depressive disorder

Design outcomes

Primary

Measure	Time frame
Effects of Ivabradine on spontaneous pain produced by Capsaicin	—

Secondary

Measure	Time frame
Effects of oral administration of Ivabradine on the thermal hyperalgesia, mechanical hyperalgesia, mechanical allodynia, and flare produced by topical application of Capsaicin	—

Countries

Japan

Contacts

Public ContactSatoshi Tanaka

Shinshu University School of Medicine Department of Anesthesiology and Resuscitology

s_tanaka@shinshu-u.ac.jp0263-37-2670

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026