Longitudinal study for Cognitive function and Brain structural changes associated with Ablation-therapy for Atrial fibrillation

Longitudinal study for Cognitive function and Brain structural changes associated with Ablation-therapy for Atrial fibrillation - Longitudinal study for Cognitive function and Brain structural changes associated with Ablation-therapy for Atrial fibrillation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000023007

Enrollment

100

Registered

2016-07-10

Start date

2016-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial fibrillation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with paroxysmal or persistent atrial fibrillation in whom a clinical decision was made to perform ablation therapy. Patients with a written informed consent.

Exclusion criteria

Exclusion criteria: (1)patients with past history of neuro-psychological disorders and significant organic diseases (2)Patients with hemorrhagic symptoms (3)Patients with coagulation defect associated with hepatic disease (4)Patients with renal failure (5)Patients with difficulty in obtaining written informed consent (6)Patients in whom physician-in-charge decides unsuitable for this study (7)Patients with difficulty in evaluating brain MRI:Patients undergoing Pacemaker-implantation, coronary artery stenting and other metal device implantation or patients with claustrophobia (8)Patients with pregnancy

Design outcomes

Primary

Measure	Time frame
(1) Cognitive function, (2)Gray matter volume, (3)Cerebral blood flow (CBF) Comparison those parameters between before and after 6 months following Ablation therapy.	—

Countries

Japan

Contacts

Public ContactYasuko Tatewaki

Tohoku University, Institute of Development, Aging and cancer Aging Research and Geriatric Medicine

yasuko.tatewaki.a7@tohoku.ac.jp022-717-8559

Outcome results