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Combination therapy of intravitreal aflibercept and topical bromfenac for RVO

Combination therapy of intravitreal aflibercept and topical bromfenac for RVO - Combination therapy of IVA and bromfenac

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000022988
Enrollment
40
Registered
2016-08-01
Start date
2016-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

retinal vein occlusion

Interventions

use of topical bromfenac use of artificial lacrimal fluid

Sponsors

Juntendo Urayasu Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)The patients who received enough explanation about the purpose of this study, was obtained its consent 2)the patients who had macula edema due to retinal vein occlusion from the onset of less than 12 months

Exclusion criteria

Exclusion criteria: 1) The patient who has difficulty in periodical going to hospital. 2)The patients who have had vitrectomy surgery or anti-VEGF injection. 3)The patient who received intraocular operation within three months before first injection. 4)The patient that it was judged to be inappropriate as an object of this study. 5)The patients who had other disease which induce visual disorder.

Design outcomes

Primary

MeasureTime frame
visual acuity at the time of 12 month from injection

Secondary

MeasureTime frame
central macula thickness at the time of 12 month from injection, injection number during 12 months

Countries

Japan

Contacts

Public ContactYoshihito Sakanishi

Juntendo Urayasu Hospital Ophthalmology

ysakani@juntendo.ac.jp047-353-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026