A study on the impact of pineapple-extracted ceramide for alleviation of the symptoms of dry mouth

A study on the impact of pineapple-extracted ceramide for alleviation of the symptoms of dry mouth - Impact of the pineapple-extracted ceramide for dry mouth

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022976

Enrollment

Registered

2016-07-22

Start date

2016-07-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

xerostomia

Interventions

Duration: 8 weeks Taking one supplement tablet containing ceramide after breakfast one time per day after breakfast for 2 weeks. After four-week washout period, taking one placebo tablet after breakf

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The person who have a feeling of dry mouth

Exclusion criteria

Exclusion criteria: Subjects who have received radiotherapy or chemotherapy. Subjects who have scheduled the extraction of teeth or the other oral surgical management. Subjects who have a history of allergic reaction with pineapple and fruit.

Design outcomes

Primary

Measure	Time frame
Subjective evaluation of dry mouth at before administration and two weeks after administration	—

Secondary

Measure	Time frame
Moisture level, saliva wetness and number and form of fungiform papilla at before administration and two weeks after administration	—

Countries

Japan

Contacts

Public ContactMamoru Murakami

Kagoshima University Medical and Dental Hospital Denture Prosthodontics Restoration

kaku@dent.kagoshima-u.ac.jp0992756222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026