Study of the efficacy and safety of intra-retinal arterial fibrinolysis for central retinal artery occlusion

Study of the efficacy and safety of intra-retinal arterial fibrinolysis for central retinal artery occlusion - Intra-retinal arterial fibrinolysis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022972

Enrollment

Registered

2016-07-01

Start date

2015-09-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Retinal Artery Occlusion(CRAO)

Interventions

To inject tPA which concentration is prepared 8000unit/0.1ml

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)More than 20-year-old 2)Patients with CRAO 3)Patients who are able to stay in the hospital 4)Patients without cardiovascular diseases 5)Patients who obtained the informed consent

Exclusion criteria

Exclusion criteria: 1)Patients who may have side effects by tPA 2)Pregnancy 3)Patients judged to be appropriate

Design outcomes

Primary

Measure	Time frame
Visual acuity 24 weeks after surgery	—

Secondary

Measure	Time frame
1) Improvement of visual acuity from baseline to 24 weeks after surgery 2) Change of retinal thickness from baseline to 24 weeks after surgery 3) Laser speckle from baseline to 24 weeks after surgery 4) Occurrence rate of surgical complications 5) Vison loss	—

Countries

Japan

Contacts

Public ContactHiroshi Inazaki

Yokohama City University Medical Center Department of Ophthalmology

ojionobao@yahoo.co.jp045-261-5656

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026