Periodontal disease
Conditions
Interventions
The subjects who do not possess gingivalis are excluded at this point in time.
Ten subjects who possess Porphyromonas gingivalis carry out toothbrushing after breakfast and lunch as usual and apply t
Sponsors
Nihon University School of Dentistry at Matsudo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Because this study is intended for the adults with periodontal disease, the physically healthy person from 30 to 70 years old
Exclusion criteria
Exclusion criteria: Pregnant women, the person with the dosage of antibiotics within the past six months, the person with diabetes, the person with stomatitism, and the person with alcohol allergy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ten subjects who possess Porphyromonas gingivalis carry out toothbrushing after breakfast and lunch as usual and apply this manicure by subject oneself according to an instruction manual each time. The first samples are collected right before the subjects apply this manicure. After they apply it consecutively for ten days, the second sample is collected on the eleventh day. By the qPCR method, determining the quantity of P. gingivalis in those samples are performed in order to investigate whether this product has an antibacterial effect on P. gingivalis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Gingival crevicular fluid samples from the subjects who consented For this study are collected using sterile paper points. After DNA extraction in the samples, having P.gingivalis or not is examined by the PCR method, and ten subjects are selected for this study. | — |
Countries
Japan
Contacts
Public ContactOsamu Tsuzukibashi
Nihon University School of Dentistry at Matsudo Department of Microbiology and Immunology
Outcome results
None listed