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Effect of pregabalin combined with NSAIDs and thoracic epidural analgesia on pain after thoracotomy in lung cancer

Effect of pregabalin combined with NSAIDs and thoracic epidural analgesia on pain after thoracotomy in lung cancer - Effect of pregabalin after thoracotomy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000022970
Enrollment
40
Registered
2016-07-01
Start date
2012-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

An epidural catheter was inserted at the T4-T5 interspace in the operating room just before starting the general anesthesia. An epidural test dose of 3mL lidocaine 10mg/mL, 5 mL ropivacaine 7.5 mg/mL
5 on the numerical rating scale: NRS), 60 mg oral loxoprofen or 25mg suppository diclofenac was administered as rescue medication. An epidural catheter was inserted at the T4-T5 interspace in the oper

Sponsors

National Hospital Organization, Kanagawa Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: lung cancer patients who can undergo lobectomy and pneumonectomy, and who epidural catheter is inserted at the T4-T5 interspace in the operating room. patients who have signed the consent form to participate in this study. patients over 20 years old when participate in this study.

Exclusion criteria

Exclusion criteria: patients with serious complications (such as asthma, renal disease, gastric ulcer), which are contraindication of NSAIDs. patients over P 3 (ECOG) patients considered unsuitable for the study by a primary physician

Design outcomes

Primary

MeasureTime frame
Pain score (NRS) after removing the thoracic epidural analgesia (TEA)

Secondary

MeasureTime frame
Daily pain score Times of oatient Controlled analgesia (PCA) injection of thoracic epidural analgesia Pain scale in the morning, evening and sleeping Occurrence rate and severity of adverse effects

Countries

Japan

Contacts

Public ContactYasoo Sugiura

National Hospital Organization, Kanagawa National Hospital General Thoracic Surgery

yasoos@hotmail.com0463-81-1771

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026