Deep brain stimulation(DBS) for intractable obsessive-compulsive disorders(OCDs). randomized crossover trial and open-label trial

Deep brain stimulation(DBS) for intractable obsessive-compulsive disorders(OCDs). randomized crossover trial and open-label trial - Deep brain stimulation for intractable obsessive-compulsive disorders (DBS for OCDs)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022969

Enrollment

Registered

2016-07-07

Start date

2016-07-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intractable obsessive-compulsive disorders

Interventions

Deep brain stimulation group Sham deep brain stimulation group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 20 to 70 year-old OCD patients diagnosed by DSM-5 with the informed consent. Y-BOCS score of 30/40 or more and Global Assessment of Functioning scores of 45 or less. Refractory against medication and cognitive behavioral therapy for more than 5 years.

Exclusion criteria

Exclusion criteria: Other psychiatric illness (autism, schizophrenia, bipolar disorders, depression, drug addiction), and brain disease (epilepsy, trauma, cerebro-vascular disease, neuro-degenerative disease) except tic and Tourette syndrome. Severe cardiac diseases, pulmonary diseases blood diseases Pregnant or during breast-feeding. Whom researchers judged as inappropriate

Design outcomes

Primary

Measure	Time frame
more than 35% improvement of Yale Brown Obsessive Compulsive Scale (Y-BOCS) at 12 months after the initiation of AIC/VS-DBS.	—

Countries

Japan

Contacts

Public ContactKenji Sugiyama

Hamamatsu University School of Medicine Department of Neurosurgery

kesugi@hama-med.ac.jp053-435-2283

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026