Comparison of vonoprazan-based dual therapy with amoxicillin and the triple therapy with amoxicillin and clarithromycin for H. Pylori Eradication

Comparison of vonoprazan-based dual therapy with amoxicillin and the triple therapy with amoxicillin and clarithromycin for H. Pylori Eradication - Comparison of Vonoprazan-based Dual and Triple Therapies for H. Pylori Eradication

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022922

Enrollment

100

Registered

2016-07-01

Start date

2016-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H. pylori infection

Interventions

Triple therapy with vonoprazan 20 mg bid, amoxicillin 750 mg bid and clarithromycin 200 mg or metronidazole 250 mg bid for 1 week. The dual therapy with vonoprazan 20 mg bid and amoxicillin 500 mg t

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients infected with H. pylori Patients who agree to participate to the study

Exclusion criteria

Exclusion criteria: Patients who do not agree to participate to the study Patients who had ever failed in eradication of H. pylori no less than 2 times. Patients who are allergic to any of drugs used in this study Patients who are considered inappropriate to participate to the study by the doctor

Design outcomes

Primary

Measure	Time frame
eradication rates of H. pylori	—

Countries

Japan

Contacts

Public ContactTakahisa Furuta

Hamamatsu University School of Medicine Center for Clinical Research

furuta@hama-med.ac.jp053-435-2850

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026