Association of genetic variation of the OPRM1 gene with perioperative opioid analgesia

Association of genetic variation of the OPRM1 gene with perioperative opioid analgesia - Association of genetic variation of the OPRM1 gene with perioperative opioid analgesia

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000022900

Enrollment

350

Registered

2016-06-27

Start date

2008-08-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Nausea and Vomiting

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Elective surgical patients with ASA-physical staus of 1 or 2

Exclusion criteria

Exclusion criteria: Patients with a history of previous PONV, liver deficiency, renal deficiency, dementia, psychiatric diseases, or chronic pain and those who were pregnant

Design outcomes

Primary

Measure	Time frame
severity of postoperative nausea and vomiting at 72hrs after surgery	—

Secondary

Measure	Time frame
pain intensity at 72hrs after surgery, analgesics consumption at 72hrs after surgery, complications at 72hrs after surgery	—

Countries

Japan

Contacts

Public ContactYukihiro Kumeta

Otaru General Hospital Anesthesia

kumeta-yu@otaru-general-hospital.jp0134251211

Outcome results