An exploratory study in developing a diagnostic method for rheumatic diseases using a photoacoustic imaging system

An exploratory study in developing a diagnostic method for rheumatic diseases using a photoacoustic imaging system - An exploratory study in developing a diagnostic method for rheumatic diseases using a photoacoustic imaging system

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022896

Enrollment

Registered

2019-09-13

Start date

2016-09-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatic diseases (rheumatoid arthritis, polymyalgia rheumatica, palindromic rheumatism, RS3PE syndrome, Sjogren&#39

Interventions

Photoacoustic Imaging (Use of the device is for up to three days)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with undifferentiated arthritis and rheumatic disease (rheumatoid arthritis, polymyalgia rheumatica, palindromic rheumatism, RS3PE syndrome, Sjogren's syndrome, psoriatic arthritis, seronegative spondyloarthropathy, systemic connective tissue disease) those who were enrolled in KURAMA cohort study. 2. Patients who aged over 20 years and older at the time of informed consent. 3. Patients who have agreed to participate in this study from their own free will with document consents.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating patients 2. Patients who takes photosensitizer for photodynamic therapy 3. Patients with a cardiac pacemaker 4. Patients who are in poor general status 5. People who have any following complications in assessment body parts: Open wounds, excoriations, acnes, surgical wounds. Infected wounds. Infections. Neurological diseases and orthopedic disorders in which it is impossible to keep sitting or standing position. 6. People who have any following history of disorders: Mental disorders. Dementia. 7. Patients who are judged ineligible to enroll into this clinical study by the investigator or the sub-investigators due to communication difficulty, limitations in taking examination position and other reasons.

Design outcomes

Primary

Measure	Time frame
Contrast and volume of photoacoustic images corresponding to synovitis (blood flow in the synovial hyperplasia) in joints, synovial bursa or tendon sheath for undifferentiated arthritis and rheumatic diseases.	—

Secondary

Measure	Time frame
Incidence of adverse events by using the photoacoustic imaging system. (Final monitoring is conducted within 90 days after intervention)	—

Countries

Japan

Contacts

Public ContactKouichi Murata

Graduate School of Medicine Kyoto University Department of the Control for Rheumatic Diseases

morifuru@kuhp.kyoto-u.ac.jp075-751-3366

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026