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A Comparative Study of Potassium-Competitive Acid Blocker (Vonoprazan) and Proton Pomp Inhibitors in Helicobacter Pylori Eradication Therapy.

A Comparative Study of Potassium-Competitive Acid Blocker (Vonoprazan) and Proton Pomp Inhibitors in Helicobacter Pylori Eradication Therapy. - H. pylori eradication therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000022891
Enrollment
1353
Registered
2016-07-15
Start date
2014-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H. pylori-positive patients diagnosed with gastric/duodenal ulcer history, MALT lymphoma, post endoscopic submucosal dissection for early gastric cancer and atrophic gastritis by upper gastrointestinal endoscopy using a high-resolution endoscope

Interventions

None listed

Sponsors

Hattori Clinic
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: H. pylori-positive patients diagnosed with gastric/duodenal ulcer history, MALT lymphoma, post endoscopic submucosal dissection for early gastric cancer and atrophic gastritis by upper gastrointestinal endoscopy using a high-resolution endoscope (GIF260, 290 series; Olympus, Tokyo, Japan) from April 2014 to December 2015 at Hattori clinic were enrolled in this study.

Exclusion criteria

Exclusion criteria: Exclusion criteria were as follows: age less than 20 years, past history of total gastrectomy, history of drug allergy to PPIs, AMPC, CAM or MNZ, clinically significant disease (hepatic, renal or cardiac disease) and pregnancy.

Design outcomes

Primary

MeasureTime frame
The primary endpoint was eradication rate from April 2014 to December 2015 at Hattori clinic.

Secondary

MeasureTime frame
The secondary endpoint was evaluation of adverse events.Adverse events were defined as undesirable medical symptoms or conditions, which Patients were interviewed at the timing of eradication determination.

Countries

Japan

Contacts

Public ContactKouichi Sakurai

Hattori Clinic Hattori Clinic

sakurai@s3.kcn-tv.ne.jp+81-96-325-2300

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026