Safety and efficacy of drug-coated balloon following Excimer laser thrombus evaporation in patients with ST-segment elevation myocardial infarction (Laser-DCB study)

Safety and efficacy of drug-coated balloon following Excimer laser thrombus evaporation in patients with ST-segment elevation myocardial infarction (Laser-DCB study) - Drug-coated balloon following Excimer laser in patients with acute myocardial infarction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022878

Enrollment

Registered

2016-06-24

Start date

2016-06-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction (ST-segment elevation myocardial infarction)

Interventions

Excimer laser thrombus evaporation is performed after initial treatment of conventional manual thrombectomy. Drug-coated balloon is used following balloon angioplasty for the culprit lesion.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Acute myocardial infarction within 24 hours from the onset

Exclusion criteria

Exclusion criteria: 1) Cardiac arrest or post-resuscitation 2) Cardiogenic shock or hemodynamic instability 3) Serum creatinine 2.0 mg/dl or above 4) Significant congestive heart failure 5) Left main trunk disease 6) Reference vessel diameter < 2.0 mm 7) No indication for percutaneous coronary intervention 8) Other conditions judged inappr opriate by the attending physician

Design outcomes

Primary

Measure	Time frame
Primary procedure succsess rate Late lumen loss Restenosis rate	—

Countries

Japan

Contacts

Public ContactDaisuke Tonomura

Shiroyama Hospital Cardiovascular Center

tonomura@shiroyama-hsp.or.jp072-958-1000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026