Evaluation study of serotonin 1B receptors in mental disorders by positron emission tomography

Evaluation study of serotonin 1B receptors in mental disorders by positron emission tomography - Evaluation study of serotonin 1B receptors in mental disorders

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022849

Enrollment

Registered

2016-06-27

Start date

2016-06-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Organic and symptomatic mental disorders, Schizophrenia, mood disorders, anxiety disorders, nonorganic insomnia

Interventions

PET ([11C]AZ20149369 370MBq), MRI, blood concentration

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Patients who diagnosed as F0, F2, F3, F4, F5 by ICD-10 - healthy control

Exclusion criteria

Exclusion criteria: - with past or current history of serious medical illness and/or brain organic diseases - subject who is contraindicated for the use of MRI - with past or current history ofsevere liver disease, kidney disease, heart disease, allergy, or severe drug allergy - pregnant woman - subject who are judged as not suitable for participation in this study

Design outcomes

Primary

Measure	Time frame
evaluation of the serotonin 1B receptor of mental disorders by PET	—

Secondary

Measure	Time frame
cognitive function by neuropsychological test, MRI, blood concentration, sleep state	—

Countries

Japan

Contacts

Public ContactAmane Tateno

Nippon Medical School Department of Neuropsychiatry

amtateno@nms.ac.jp+81-3-3822-2131

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026