Rheumatoid Arthritis
Conditions
Interventions
None listed
Sponsors
University of Occupational and Environmental Health, Japan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Eligible patients were diagnosed with RA, as defined by the ACR 1987 criteria or ACR/EULAR 2010 criteria.
Exclusion criteria
Exclusion criteria: Patients were excluded if they had history of demyelinating or convulsive disease of the central nervous system (e.g., multiple sclerosis and epilepsy), New York Heart Association Class III or IV congestive heart failure, infectious disease, hepatitis B or hepatitis C, malignant tumor or lymphoproliferative disorder, including lymphoma or signs and symptoms suggestive of lymphoproliferative disease. Patients with any indication of current or past tuberculosis as shown by clinical history, chest X-ray and/or positive tuberculin reaction test were also excluded unless preventive therapy by isoniazid was first taken.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of DAS28-ESR at 12weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Change of DAS28-ESR at 24 hours, 48hours and 24weeks (2) Remission rate of DAS28 and CDAI at 24 hours, 48hours, 12 weeks and 24weeks (3) Adverse event (4) The factors for each outcomes | — |
Countries
Japan
Contacts
Public ContactKazuhisa Nakano
University of Occupational and Environmental Health, Japan The First Department of Internal Medicine, School of Medicine
Outcome results
None listed